This review examined how genetic differences in taste receptors may influence taste perception, eating behaviours, food preferences, and health outcomes. The authors explored how variations in genes related to fat, sweet, bitter, umami, and salt taste may contribute to differences in dietary patterns and chronic disease risk.

What We Did and Why We Did It

Researchers reviewed existing studies on single nucleotide polymorphisms (SNPs)—small genetic variations that can affect how taste receptors function. The review examined genes involved in detecting different tastes, including the CD36 receptor for fat taste, T1R2/T1R3 receptors for sweet taste, T2R38 for bitter taste, T1R1/T1R3 for umami taste, and ENaC/TRPV1 for salt taste. Researchers summarized evidence linking these genetic differences to taste sensitivity, food preferences, eating behaviours, and health outcomes.

People experience food differently, and taste plays an important role in shaping what foods we enjoy and choose to eat. While food preferences are influenced by culture, environment, and experiences, genetics may also contribute to differences in taste perception. Understanding how genes influence taste could help researchers develop more personalized approaches to nutrition and better understand factors that contribute to chronic disease risk.

What We Found

What We Can Learn From This

Genetic variations in taste receptors were linked to differences in how individuals perceive and respond to certain foods. Variations in the CD36 fat taste receptor may influence sensitivity to dietary fats and preferences for high-fat foods. Differences in sweet taste receptors were associated with sugar preferences, intake, and outcomes such as dental caries and BMI. Variations in the bitter taste receptor T2R38 may affect sensitivity to bitter foods, with some individuals avoiding bitter vegetables and potentially consuming more sweet or fatty foods. Genetic differences related to umami and salt taste were also identified, although more research is needed to understand their effects on eating behaviours and health.

Our genes may influence how we experience food, which can shape our preferences and eating behaviours. However, genetics is only one factor that affects diet—family habits, culture, food availability, and personal experiences also play important roles. Understanding differences in taste perception may help researchers create nutrition approaches that better consider individual needs and preferences.

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